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Many solid tumors show little to no response to ICIs or develop acquired resistance, largely due to the immunosuppressive state of the tumor microenvironment, often referred to as cold tumors [356]

This is evidenced by increases in lipid peroxidation, glutathione oxidation, and oxidative protein damage

J Hepatol (2021) 75:2224

By targeting the brain's hunger signals, they reduce appetite and increase satiety, aiding in sustainable weight management and healthier eating habits

Correlation of pretreatment p63-positive subtype of gastroesophageal adenocarcinoma (GEAC) with pathologic complete response (pathCR) in patients receiving preoperative chemoradiation

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