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[DOI] [PubMed] [Google Scholar] [6].Bannai S, Christensen HN, Vadgama JV, Ellory JC, Englesberg E, Guidotti GG, et al

Antioxidant Supplementation in Atherosclerosis Prevention (ASAP) study: a randomized trial of the effect of vitamins E and C on 3-year progression of carotid atherosclerosis

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doi: 10.1126/science.279.5357.1718

Acronyms and abbreviations European union joint programme-neurodegenerative disease research glutathione disulfide glutathione peroxidase glutathione S-transferase glutathione synthetase glutathione reductase Parkinsons disease Alzheimers Disease neurodegenerative diseases reactive nitrogen species reactive oxygen species reduced glutathione oxidative stress 4-hydroxyl 2, 3-nenonal excitatory amino acid transporter C1 excitatory amino acid transporter -glutamylcysteine synthetase neurofibrillary tangles References 1

In a model of Nrf2 / null mice subject to partial ischemia and reperfusion, the expression of several Nrf2-dependent genes was compromised, including GSTm1, NQO1, and GCL, resulting in the worsening of the redox state in comparison with livers from wild-type mice [218]