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Polyamine-Based Thiols in Trypanosomatids: Evolution, Protein Structural Adaptations, and Biological Functions

7D), suggesting the lack of noticeable toxic effects

By correcting for possible imbalances, we aimed at reducing infection-related gastric pathologies

The presence of adequate circulating T 4 and T 3 feeds back at the level of both the hypothalamus and pituitary, decreasing TRH and TSH production ( Figure 2 )

Using a highly selective inhibitor against IP6K, which could be administered and examined in vivo, the present study demonstrates the contribution of IP6K-mediated cellular phosphate export on circulating phosphate concentrations in mammals

This was associated with the nuclear translocation of Nrf2 and an increased cellular uptake of cystine, which is the source of intracellular cysteine for GSH production