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The Global Adherence Project (GAP): a multicenter observational study on adherence to disease-modifying therapies in patients with relapsing-remitting multiple sclerosis

The study was performed in accordance with the Declaration of Helsinki

The people at risk of getting low levels of B12 are: Vegans and vegetarians as its not in their diet Over 60s as they have reduced absorption within the gut Anti acid medication or metformin Chronic digestive disorders such as Crohns, celiac disease or IBS Eating disorders or people who have had weight loss surgery Drink alcohol or abuse nitrous oxide People who are HIV positive There are different types of synthetic vitamin B12

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Although conducted in a small patient population, preliminary results (Figure 1 and Table 4) suggest that opiorphin inhibits seminal NEP and may improve sperm motility parameters