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In this respect, an interesting study conducted on immortalized human microglia cells (CVCL_5G94) highlighted how ATRAs can increase the heat shock protein 90 (Hsp90) expression on the surface of these cells, causing an increase in the amount of endocytosed and consequently eliminated tau protein (25)
doi: 10.1177/0885066620980399 Luis Caraballo, Shayan Mahapatra, Ves Dimov, Frank J Eidelman
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results, never develop symptoms of CTD
