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An in vitro study using AD fibroblasts revealed a reduction of oxoglutarate dehydrogenase activity and it was further supported by an in vivo study with AD patients whereby the activity of oxoglutarate dehydrogenase complex was markedly reduced by 46 to 68% [201, 202]

In clinical studies, many participants lost between 15% and 20% after 72 weeks of treatment alongside healthy eating and regular activity

Meat Sci 116:186192

doi: 10.1016/S0027-5107(98)00104-3

Podlesakova K, Ugena L, Spichal L et al (2019) Phytohormones and polyamines regulate plant stress responses by altering GABA pathway

Nitric oxide (NO) synthase (NOS) pathway NO pathway dysregulation is important cause of endothelial dysfunction and vascular disease (71, 72)