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Therefore, patients' liver function should be closely monitored, and patients who clearly respond to PN should continue with PN therapy, and the addition of the PNPO cofactor riboflavin may improve the activity of residual PNPO [14]

According to clinicians such as Jarred Mait, MD, the focus is not on pairing peptides by default, but on determining whether each compound aligns with an individual patients goals, injury profile, and overall health status

Small intestinal bacterial overgrowth (SIBO) is when you have an overgrowth of bacteria, and this utilises vitamin B12 and can lead to deficiency
Or is it to do with the sheer amount of work B12 has to do in the body