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These receptor proteins are characterized by the presence of LIR motifs for the interaction with ATG8 family proteins such as LC3 on the surface of phagophores, and many have ubiquitin-binding domains capable of recognizing ubiquitinated cargo, thus establishing a bridge between the cargo and the autophagic machinery (40, 92, 93)

An Integrative Medicine Guide to Ulcerative Colitis

(2017) 77:CT140
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Both of those scenarios can lead to higher B12 levels

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