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[DOI] [PMC free article] [PubMed] [Google Scholar] 48.Anandatheerthavarada H.K., Biswas G., Robin M.A., Avadhani N.G

Then literatures reported the Ala177Val mutation has no influence on the kinetic parameters of bacterial MTHFR, but rather reduces enzyme stability and affinity for cofactor, and thus increases the tendency to form inactive enzyme via flavin dissociation, compared to the wild-type enzyme 27

This state is called oxidative stress (see Chapter 45) and can result in serious cell damage if the stress is massive or prolonged

What is the appropriate vitamin B12 dosing regimen for an alcoholic patient presenting with confusion and a serum B12 level of 156 pg/mL?

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PMID: 2 FindeisenKEGuymerEKLittlejohnGO