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Bjorklund et al., 2018

Effect of the human SOD1-G93A gene on the Nrf2/ARE signaling pathway in NSC-34 cells

& Anders, M

Currently, sulfated phosphatidyl-ethanolamine hydroperoxide (SAPE-OOH) on the surface of ferroptotic cells is recognized as an eat-me signal, facilitating interaction with Toll-like receptor 2 (TLR2) on macrophages (129)

Thus, in addition to lactate production, some pyruvate is also oxidized into acetyl CoA and enters the TCA cycle, not to obtain ATP but to capture intermediate compounds to use as biosynthetic precursors

[DOI] [PubMed] [Google Scholar] 39.Franco R., Schoneveld O.J., Pappa A., Panayiotidis M.I