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take at night or reduce dose) Flushing or facial warmth Appetite suppression (desired in some cases) Fatigue or dizziness (rare) Less Common: Darkening of freckles or moles (especially in fair-skinned users) Hyperpigmentation of scars or birthmarks Spontaneous erections (especially in males at higher doses) Contraindications: History of melanoma or atypical nevi Active hormone-sensitive cancers Uncontrolled autoimmune flares without provider oversight Clinical Case Examples Case 1: Safe Tanning and Photosensitivity A 30-year-old female with light skin and lupus-associated photosensitivity followed the tanning protocol

Manoel EA, Ribeiro MFP, dos Santos SCS, Coelho MAZ, Simas ABC, Fernandez-Lafuente R, Freire DMG (2015) Accurel MP 1000 as a support for the immobilization of lipase from Burkholderia cepacia : application to the kinetic resolution of myo-inositol derivatives

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10.1124/jpet.111.181297 45 KawashiriT.EgashiraN.KurobeK.TsutsumiK.YamashitaY.UshioS.et al (2012)

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Strikingly, significantly reduced tumor cell proliferation was noted in tubular elements in some, but not all ILBC specimens