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2.8 Biochemical analysis of liver function parameters Commercial assay kits (Nanjing Jiancheng Bioengineering Institute, China) were used to evaluate the concentrations of alanine transaminase (ALT), aspartate transaminase (AST), total cholesterol (TC), triglycerides (TG), and non-esterified fatty acids (NEFA) in homogenates of mouse liver, in accordance with the prescribed procedural guidelines

Many clinicians check serum valproate levels to guide dosing and assess adherence

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However, under certain pathological conditions, excessive changes in organ weight due to organ congestion and oedema, hyperplasia and hypertrophy, atrophy or degeneration will occur