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Nat Rev Endocrinol 20 , 474486 (2024)

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The fall in progesterone during the late luteal phase initiates a controlled inflammatory response within the endometrium, characterized by the influx of leukocytes, production of cytokines and prostaglandins, and activation of matrix metalloproteinases that mediate tissue breakdown and subsequent repair (Maybin and Critchley, 2015)
