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There are several enzyme systems that catalyze reactions to neutralize free radicals and reactive oxygen species

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Polyphenols : Found in fruits, vegetables, and green tea, they possess antioxidant properties and may support methylation

The effects on plasma L-arginine levels of combined oral L-citrulline and L-arginine supplementation in healthy males. Bioscience, Biotechnology, and Biochemistry

For brain applications specifically, the gut-brain axis connection is significant
