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This is not because it is unsafe to have one more often than this, but that it is more in line with the normal dosing regimens for treating people with deficiencies

Learn what are the reasons for B12 deficiency in vegan diets in this article

Reporting summary Further information on research design is available in the Nature Research Reporting Summary linked to this article

Compounded medications provide for customization of strengths and volumes, as determined necessary by the prescribing physician for the identified patient, that may not be available in commercial products

Below that, you're paying for a compound diluted with synthesis byproducts

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