lingual melanotic macules of the tongue in a newborn Pigmented Oral Lesions: Clues to
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& Landfester, K

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The spots produced by PIH are typically brownish, sometimes with a grayish undertone, and they can take months to fade on their own
85 In the MOG-associated variant of the disease auto-antibodies attack oligodendrocytes thus causing their death and secondary astro- and microgliotic response

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Recent evidence suggests there is also likely an HDL-independent pathway for systemic cholesterol removal through transintestinal cholesterol excretion (TICE) (711)
