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It is also very necessary to identify if TMAO contributes to chondrocytes injury through modulating the classical pathways of ferroptosis such as ACSL4/GPX4 or other specific pathways, such as those of iron-related proteins, lipid peroxidation products, and other sensitivities to mechanical stimulation

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and social welfare for an economy E comprising N consumers, evaluated at a resource allocation q = (q 1 ,,q N ) for these N consumers, is measured by a social welfare function W(U1(q 1 ),,UN(q N )) satisfying the following monotonicity property: W is a strictly increasing function of the utility level Uj(q j ) attained by consumer j, all else equal, for each j = 1,,N

For quantitative analyses, 1 fmol of p 7 /soto-p 7 and 5 fmol of p 8 /soto-p 8 were spiked into cell lysates prior to immunoprecipitation