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M.BoelensH.SluijterM.LuijendijkA.RumkeH

J.DimmenA

NAC has been at the center of attention due to its effectiveness in some pathologies and diseases in humans such as the prevention of chronic obstructive pulmonary disease (COPD) exacerbation [18], prevention of contrast-induced nephropathy during the imaging process [19], improving the health condition in influenza virus infection, and improving cell-mediated immunity [20], and promising treatment of pulmonary fibrosis [21]

Induction of interleukin-9-producing mucosal mast cells promotes susceptibility to IgE-mediated experimental food allergy

A.HaddadP

Replacement of Asn450 by glutamine (N450Q), aspartate (N450D), and alanine (N450A) showed a significant increase in transpeptidase activity up to 3.6-fold enhancement and minor maturational defects, suggesting significant contribution of this residue in substrate binding and catalysis