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A 2021 review cites older research that suggests regular vaginal distribution of DHEA may improve symptoms of vulvovaginal atrophy in postmenopausal women
Cheng et al., 2015)

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Coleman ML, et al

J Pharm Pharmacol 76:11991211 Depoortre R, Dargazanli G, Estenne-Bouhtou G, Coste A, Lanneau C, Desvignes C, Poncelet M, Heaulme M, Santucci V, Decobert M (2005) Neurochemical, electrophysiological and pharmacological profiles of the selective inhibitor of the glycine transporter-1 SSR504734, a potential new type of antipsychotic

doi:10.2174/1570159X19666201230144109