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Disruption of lung iron homeostasis appears to be involved in several lung diseases and we therefore looked for evidence of ferritinophagy, which describes a form of selective autophagy characterised by degradation of intracellular ferritin mediated by nuclear receptor coactivator 4 (NCOA4), which increases intracellular iron levels leading to accumulation of lipid ROS and ultimately cell death [52]

Sampson also appointed a new team of leadership to reinforce the schools mission and help reach his goal of Top 10 in 10 Years. To end another successful year at the CU Anschutz School of Medicine, take a look back at some of the top coverage and news made by students, researchers, and faculty members

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7.6 Other drugs potentially useful in vitiligo Metformin, a widely used anti-diabetic drug, is gaining attention for its role in treating immune-mediated disorders due to its immunomodulatory and anti-inflammatory properties ( Fibrates are a class of drugs primarily used to manage dyslipidemia that activate the PPAR- ( Given their well-established use in cardiovascular medicine and their favorable safety profile, fibrates could emerge as a novel adjunctive therapy for vitiligo, especially in patients with coexisting lipid abnormalities or metabolic syndrome