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A test set of disease- and non-disease-associated variants To define a set of disease-associated CBS variants, we considered 86 unique missense variants in the CBS mutation database [22] that were not linked to a second variant in the same allele

Akt induces enhanced myocardial contractility and cell size in vivo in transgenic mice

OA Cancer 2014

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SuperScript Reverse Transcriptase (thermoscientific) was then used to generate the first-strand cDNA in accordance with the manufacturers directions 43

Meanwhile, DELs that contain covalent warheads have been recently developed for discovery of covalent inhibitors of target proteins as well 34