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It also reduced the rate of DPC apoptosis (cell death) and increased the ratio of Bcl-2/Bax (pro-survival markers)

Parlesak A 1 , Bode C, Bode JC
The standard injection dosage of 1 to 2 mg per day, subcutaneously, five days per week, covers most therapeutic goals

For IGF, the IGFR can directly activate PLC also leading to the above signaling cascade

Patients may also wonder which therapies have the strongest evidence

While many anecdotal success stories suggest it can be a valuable tool in a regenerative medicine toolbox, it is still under ongoing investigation
