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This could indicate that the greater volume of the 45S5 BG filler particles on the surface of the composite specimen led to their higher exposure to water and dissolution, thus widening the open pores and reducing its number

Human data is still limited, so results vary and it's used under supervision

Colistin was introduced in the clinic in 1961 with the expectation, by the scientific community, of finally filling the void in the treatment of challenging infections such as those from antibiotic resistant Pseudomonas aeruginosa [4]

these treatments are not universally available to all patients