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Description
Enhanced cytotoxicity of bioreductive antitumor agents with dimethyl fumarate in human glioblastoma cells
Injection and IV routes may deliver a substance directly into the body, but they also create additional concerns when products are contaminated, improperly compounded, or administered by an unqualified person
This accumulation contributes to syn pathology through multiple mechanisms
Treat by compartment, matching drugs and delivery to the exact localemitochondrial matrix or IMS, ER lumen, peroxisome, or plasma-membrane microdomainswhere the reactive chemistry originates and use biomarkers to time and titrate (Giacomello et al
doi: 10.1371/journal.pone.0225598
BMC Chemistry, 17(1), 68
