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The introduction of FDA-approved pharmaceutical grade IGF-1 products in the form of Increlex and Iplex is likely to have seen an increase in rhIGF-1 abuse by athletes [97] and in the years that followed a number of newer IGF-1 compounds, analogues and products also became available, some even to the general public [98,99]

This process requires meticulous surveillance of adverse events throughout clinical trials and comprehensive safety verification for each individual strain (563)

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Veterinarians sometimes elect to speed up this process