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Animal LD50 studies showed toxic levels around 320 mg/kg body weight, translating to approximately 22,400 mg for a 70 kg human

The RNA binding protein CsrA controls c-di-GMP metabolism by directly regulating the expression of GGDEF proteins

The dosing and the duration shift with the operation

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By blocking TREK-1 channels, PE-22-28 restores normal neuronal excitability in circuits critical for mood regulation

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