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Hence, senolytic therapies may be a suitable approach for increasing therapy sensitivity and preventing cancer relapse 10

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This process avoids adding external molecules since interferon gamma (IFN-) and tumor necrosis factor-alpha (TNF-), two cytokines associated to the SASP, act as natural adjuvant by promoting an immunoreaction

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In addition, there was an increase in nitric oxide, IL-1, IL-6, and TNF- production in mouse retina [108]