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Overexpression of FtMt reduced osteoblastic ferroptosis and improved osteoblast function under HG conditions, whereas knockdown of FtMt decreased osteogenic function and induced mitophagy through the ROS/PINK1/Parkin pathway (67)

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SLC7A11 expressions positively correlate with insensitivity to HDACIs in many types of cancer cell lines (Fantin and Richon, 2007)

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However, aging, pollution, stress, and poor lifestyles can cause a depletion of these natural levels
