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Anyone with a known copper allergy, open wounds or broken skin at the application area, or who is pregnant or breastfeeding
10.3892/ijo.2016.3602 36 FukushimaT.UchiyamaS.TanakaH.KataokaH
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A deficiency in Vitamin B12 can lead to symptoms such as tiredness, weakness, anaemia, and cognitive issues
Conversely, zinc deficiency or chelation of tissue zinc improves anti-tumor immunity and enhances responses to immunotherapies such as PD-1, particularly in melanoma models [328]
