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For example, the putative solute transporter MFSD12 negatively regulates pigmentation from lysosomes (Crawford et al., 2017) and NCKX5 encoded by SLC24A5 , the gene deficient in OCA6, appears to positively regulate pigmentation from the trans Golgi network (Ginger, Askew et al., 2008, Rogasevskaia, Szerencsei et al., 2019)

PLoS ONE 9(7): e100627

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Juveniles are patterned with reddish-brown spots with a gray or brown body, resembling young rat snakes, and gradually darken to solid black with age

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In adult patients receiving TPN, the lack of carnitine in nutrition solutions contributes to deficiency, impacting fatty acid oxidation
