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Development of small-molecule BRD4 degraders based on pyrrolopyridone derivative

L-theanine intake (6 mg/kg) could prevent brain atrophy and stress vulnerability in senescence-accelerated mice prone 10 (SAMP10) mice, with the mechanism of intaking L-theanine could block the expression changes of the transcription factor neuronal PAS domain protein 4 ( Npas4 ) and Lipocalin 2 ( Lcn2 ) in hippocampus and PFC of SAMP10 (58)

doi: 10.1016/j.fsi.2022.01.037

Kovalcsik R, Devlin T, Loux S, Martinek M, May J, Pickering T, et al

However, this review will focus on a few models illustrating the mechanisms of intrinsic cases of DILI

L.JungY
