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Management of immunotherapy-related toxicities, version 1.2022, nccn clinical practice guidelines in oncology
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BER enzymes are primarily targeted at removing N7-MeG and N3-MeA lesions, subsequently repairing the DNA through the collaborative action of DNA polymerase and DNA ligase, thus restoring the DNA strand to its original, non-damaged state [165]
& Miyazaki, A
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