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Description BPC-157 is studied for its role in cellular signaling related to tissue integrity in tendon, ligament, and GI-lining research models

doi: 10.1016/j.cyto.2013.03.011 61 BunpoPDudleyACundiffJKCavenerDRWekRCAnthonyTG

J.BowerC.PettersonB.de KlerkN.ChaneyG.HallmayerJ

In an experimental study carried out by Chen Y et al., 2018, it was determined that, in Sprague Dawley rats fed a High fat diet (HFD) during 12 weeks, the authors demonstrated that APS1 significantly reduced body weight and also reduced the accumulation of hepatic lipids regulating the expression of SIRT-1/PGC-1/SREBP-1, as well as the increase in hepatic antioxidant activity on modulating the expression of activity of NRF-2 and HO-1 [51]

doi: 10.1016/j.bbr.2019.112080 84

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