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Description
In schizophrenia (SZ), Down Syndrome, and bipolar disorder (BD), increased brain insulin resistance and reduced IGF-1 signaling drive allostatic load/overload, leading to physiological dysregulation and the presentation of more severe symptoms throughout the body [44,45,46]
the enzyme's activity responds to sustained suppression over days and weeks, not single-dose precision

JCI Insight 5 , e135751 (2020)

However, none of these candidates could be confidently assigned as canonical catalase homologs based on sequence similarity criteria

These data demonstrate that RSSH and/or COS can provide protection when given at reperfusion in hearts subjected to I/R injury

WW, MZ, TZ, HC and RT contributed to the acquisition, analysis and interpretation of data
