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It is a cytoplasmic danger sensor that recognizes stress stimuli, such as ROS, ATP, and ionic flux, and induces the processing and secretion of pro-inflammatory cytokines, specifically IL-1 and IL-18, which promote inflammation and are responsible for renal tissue fibrosis [145]

Effects of dioscorea nipponica on the expression of Th17/Treg cytokines in patients with hashimoto thyroiditis

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McGill, R., Tukey, J

22 September 2025

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