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In the Multi-Ethnic Study of Atherosclerosis, when LDL-C and LDL particle number were discordant, incident cardiovascular disease and carotid intima-media thickness tracked more closely with LDL particle number than LDL-C (Otvos et al., 2011)

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10.1016/j.bbr.2016.06.012 169 LeeS

Larger individuals with more adipose tissue benefit from doses at the upper end of standard ranges
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