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In addition, we found that the conjugate of HNE to cysteine was produced in much lower yield than HNE-GSH, while that of N-acetylcysteine could not be detected

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Additionally, the review highlights the utility of PLGA nanoparticles in delivering phytochemicals with neuroprotective effects such as polyphenols, flavonoids, and coumarins to overcome challenges associated with their solubility and stability and ultimately enhance their activities for managing PD.

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