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In addition, patients who have Hashimotos thyroiditis are at an increased risk of developing other autoimmune disorders, including these: Type 1 diabetes mellitus: The body produces little or no insulin or the insulin produced does not work as it should (insulin resistance)

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doi: 10.1016/j.freeradbiomed.2005.04.020 27 MandaranoAHMayaJGiloteauxLPetersonDLMaynardMGottschalkCGet al

Rapamycin exerts anti-ferroptotic effects by decreasing transferrin receptor expression, reducing cellular iron content, and activating the iron-regulated protein-1/2 (Irp1/2) system, potentially compensating for transferrin downregulation to maintain iron homeostasis (69)

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Patients are usually instructed to abstain from alcohol or smoking, as these may lower the efficacy of the antioxidant