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Indeed, ErbB2 gene amplification is one of the most frequent genetic events in breast cancer, resulting in the overexpression of HER2, which promotes cell proliferation predominantly through the activation of the mitogen-activated protein kinase (MAPK) pathway

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10.1586/1744666X.2014.894886 82 RyuJ.-H.YangS.ShinY.RheeJ.ChunC.-H.ChunJ.-S

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