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Biologic and pharmacologic regulation of mammalian glutathione synthesis

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Specifically, it upregulates TGF-beta1, TGF-beta2, and Smad7 expression

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Animal studies spanning over 20 years show gastric ulcer healing, tendon repair, muscle regeneration, and neuroprotection with minimal toxicity, even at doses 10 to 100 times the therapeutic range (Sikiric et al., Curr Pharm Des 2018)

Additionally, many studies have been conducted outside the UK, and results may not directly translate to NHS patient populations