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174 Given the crucial role of GSH as a key cellular antioxidant, ferroptosis induced by GSH depletion was achieved using arginine-rich manganese silicate nanosystems (AMSN) in liver cancer cells in vitro (Huh7) and in vivo (BALB/c nude mice)

Until rigorous clinical studies confirm its efficacy and safety, BPC-157 should be approached with caution and reserved for research settings rather than mainstream therapeutics

Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death

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Representation of Women in Society of Thoracic Surgeons Authorship and Leadership Positions

Reduces oxidative stress associated with aging