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Sousa SB, Lambot-Juhan K, Rio M, Baujat G, Topouchian V, Hanna N, et al

The formation of AGEs elevates the likelihood of aggregations or cross-linkages between proteins, affecting crystallins [36], and it can further amplify oxidative stress by impairing the function of antioxidant enzymes [37]

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This difference was particularly striking within the mitotic region, where MPK-1 was about 5-fold lower in Tum+FBF than in TumFBF germlines (Figure 2B2F)