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Moreover, ALC and NAC mitigate Nf-kB overactivated signal, attenuating NLRP3 inflammasome pathway (IL1 and IL18) and decreasing serum TNF-alpha, IL-1, IL-6 levels, and PCR [161, 202, 217], thereby their immunomodulatory activities [161, 227, 228], and protecting against cytokine storms [82, 135, 218]

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However, quinolinic acid is an agonist of NMDA (74, 75)

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[DOI] [PMC free article] [PubMed] [Google Scholar] Chen HJ, Lin WP, Chiu SD, Fan CH

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Objective: To explore nurses knowledge, perceptions, and challenges of caring for mechanically ventilated patients with light sedation in adult ICUs in the United Arab Emirates (UAE) where the fixed RN to patient ratio is 1:2

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