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SakhiAKRussnesKMThoresenMBastaniNEKarlsenASmelandSet al

The PEACE-6 trial is randomizing patients with de novo or metachronous mHSPC, focusing on therapy de-escalation for good responders (undetectable PSA at 68 months) and treatment intensification for poor responders

However, C4 levels in IBS-D are not significantly correlated to mucosal permeability as assessed by urinary excretion of lactulose/mannitol, and in 23 patients with IBS-D, treatment with colesevelam tended to improve stool consistency but did not alter mucosal permeability as assessed by lactulose/mannitol excretion (173)

Culture conditions M9Y medium was used for maleate production in 5-mL test tube-scale cultures

Side effects are rare and typically mild: temporary injection site soreness, slight redness, or minor bruising

Pembrolizumab As Second-Line Therapy in Patients With Advanced Hepatocellular Carcinoma in KEYNOTE-240: A Randomized, Double-Blind, Phase III Trial