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ACS Chem Neurosci (2017) 9(4):82437

Carnitine may be helpful for: Aging Improving mental function in older adults with mild cognitive impairment and Alzheimers disease Cardiovascular and peripheral arterial disease Fatigue resulting from chemotherapy, radiation treatment, and poor nutrition in cancer patients Type 2 diabetes Human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS) Anemia management in end-stage renal disease and hemodialysis There is no evidence to support the use of carnitine for the following conditions: Athletic performance Male infertility Talk to your doctor before taking carnitine supplements

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C16-carnitine affects the insulin signaling pathway by activating PTP1B and reducing the phosphorylation of InsR Tyr1151 and Akt Ser473, thereby playing a role in the occurrence of insulin resistance [128]