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The rotamer library file was then integrated into Rosetta to ensure that the side-chain conformational space of the pAcF is sampled appropriately during simulations

The nanoparticles are incorporated into porous PLGA microcapsules to form a dry powder with a suitable aerodynamic size

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In conclusion, oxidative stress acts as a catalyst for deterioration of AD by augmenting MMP activation, thereby reshaping the ECM and aggravating degradation and remodeling of aortic wall

Studies have shown that edaravone reduces the accumulation of hydrogen peroxide (H 2 O 2 ) through upregulation of Peroxiredoxin-2 (31), and can also trap hydroxyl radicals (