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The stress-induced ROS can have effects on gene expression which may be imparted through a mitogen activated protein kinase (MAP) cascade for transcriptional regulation

Ramautar R, Berger R, van der Greef J, Hankemeier T (2013) Human metabolomics: strategies to understand biology

Advanced glycation end products, their receptors and diabetic angiopathy

10.1038/s41385-018-0021-8 6 BarbosaP.Abo El-MagdN

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For example, women with Hashimoto's thyroiditis receiving selenium reported better emotional regulation and cognitive clarity in addition to biochemical changes (198)