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Under normal conditions, the urea cycle (ornithine cycle) serves as the primary mechanism for ammonia detoxification, particularly in hepatocytes (100)

Martn-Venegas R

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Comprehensive whole-genome and candidate gene analysis for response to statin therapy in the treating to new targets (TNT) cohort

Treatment with an iron chelator eliminated both protein nitration and liver injury in the absence of LPO [80], suggesting again that under normal conditions, APAP-induced cell death is unlikely to involve ferroptosis [80]

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