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(2023) demonstrated that moderate Drp1 upregulation in ALS Drosophila models restores physiological mitochondrial distribution within axons, enabling efficient mitochondrial trafficking to nerve terminals and thereby meeting axonal energy demands

By contrast, viral proteins, ex HIV Tat, gp120, and protease, are generally produced under less than optimum circumstances because the intracellular environment of a viral infected cell, that is activated and responding, is chaotic, with compromised bioenergetics and host responses that include nitric oxide from NFKB induced iNOS

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and the effect of copper and zinc deficiency on its actiyity

1d), in visual growth kinetics (Fig

Gut 57, 747754 (2008)