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Meta-analyses of randomized controlled trials indicate that supplementation significantly improves insulin sensitivity, as reflected by reduced HOMA-IR

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On Day 21, rats in the l-carnitine group received l-carnitine orally at a concentration of 100 mg/kg of rat weight, once a day, for 4 weeks [22]

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The endogenous production of creatine and enzymes such as arginine: glycine amidinotransferase (AGAT) is responsible for its production, which is facilitated in the kidney [71,72]

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